VSIG4 HEK293
CBP74603
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| I. Background | |
| VSIG4是一种由VSIG4基因编码的免疫调节蛋白，属于B7家族相关蛋白。它的核心功能是作为补体受体CRIg，结合补体片段C3b和iC3b以清除病原体，同时作为T细胞反应的负调控因子，抑制T细胞活化和IL-2的产生，参与维持免疫稳态。在临床方面，VSIG4与炎症调控、肿瘤转移、自身免疫性疾病（如狼疮肾炎）和动脉粥样硬化等病理过程密切相关。 | |
| II. Description | |
| VSIG4 HEK293细胞，在 HEK293细胞的基础上，稳定表达 VSIG4 。 | |
| III. Introduction | |
| Expressed gene: | VSIG4 |
| Host Cell: | HEK293 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+100 μg/ml Hygromycin B |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
 Figure 1. Recombinant VSIG4 HEK293 constitutively expressing VSIG4. |
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